Boneguard® Resorbable Membrane

GBR, as described in the 1980s, consisted of using a rigid membrane to stabilise the blot clot (find out about the Graftek range non-resorbable membrane) and to enable the osteogenic cells to colonise and regenerate the space created by this membrane. Later, use of biomaterials (such as BIOBank allogeneic bone powders), enabled support of this membrane, which was no longer required to be rigid, to leave space for less restrictive resorbable membranes (no placement of material to be planned).

Meeting this indication, the BoneGuard^® membrane consists of highly purified cross-linked porcine collagen for better control of resorption time. BoneGuard^® has a “barrier effect” of over 12 weeks.

The BoneGuard^® membrane is available in one size only: 30 * 20 mm.

Prior to use, the resorbable BoneGuard^® membrane requires rehydration in a saline solution for around 5 minutes. This enables it to regain its flexibility.

It is completely reversible so has no “bone side” and “mucosal side” faces.

Due to its resistance, it may be screwed (find out about Graftek membrane screws), pinned, or sutured with no risk of tearing.

^Références

^{(1) H. Fellah, S. Kimakhe, G. Daculsi, P. Layrolle, “Macro/Microporous Biphasic Calcium Phosphate Cylinders and Resorbable Collagen Membranes for Guided Bone Growth”, Key Engineering Materials, Vols. 361-363, pp. 439-442, 2008}

^{(2) Jégoux F, Goyenvalle E, Cognet R, Malard O, Moreau F, Daculsi G, Aguado E., Mandibular segmental defect regenerated with macroporous biphasic calcium phosphate, collagen membrane, and bone marrow graft in dogs., Arch Otolaryngol Head Neck Surg. 2010 Oct;136(10):971-8}

^{(3) Jegoux, E. Goyenvalle, E. Aguado, R. Cognet, F. Moreau, G. Daculsi, “Periostal Reconstruction Using New Porcine Microstructured Collagen Membrane and Calcium Phosphate Cement: A Dog Model”, Key Engineering Materials, Vols. 396-398, pp. 257-260, 2009}

^{(4) Jégoux, F., Goyenvalle, E., Cognet, R., Malard, O., Moreau, F., Daculsi, G. and Aguado, E. (2009), Reconstruction of irradiated bone segmental defects with a biomaterial associating MBCP+®, microstructured collagen membrane and total bone marrow grafting: An experimental study in rabbits. J. Biomed. Mater. Res., 91A: 1160–1169}

^{(5) Jegoux, E. Aguado, R. Cognet, O. Malard, F. Moreau, G. Daculsi, E. Goyenvalle, “Repairing Segmental Defect with a Composite Associating Collagen Membrane and MBCP® Combined with Total Bone Marrow Graft in Irradiated Bone Defect: an Experimental Study in Rabbit”, Key Engineering Materials, Vols. 361-363, pp. 1245-1248, 2008}

^{(6) Jegoux F, Aguado E, Cognet R, Malard O, Moreau F, Daculsi G, Goyenvalle E., Alveolar ridge augmentation in irradiated rabbit mandibles., J Biomed Mater Res A. 2010 Jun 15;93(4):1519-26.}